WT1 [rWT1/857] - Concentrate - 0.1 ml

Product Description

WT1 is a gene involved in the induction of Wilms’ tumour. In normal human tissues, WT1 mRNA has been observed in kidney, spleen and gonadal ridge mesoderm. WT1 expression has also been observed in sertoli cells of testes and in granulosa cells of the ovary. In tumours, WT1 has been demonstrated in Wilms’ tumours and in the majority of mesotheliomas (nuclear and paranuclear staining). WT1 has also been demonstrated in the majority of acute leukaemia’s, but not in cells from chronic myelogenous leukaemia. Cytoplasmic staining has been observed in some cases of adenocarcinoma and may represent cross reactivity with an epitope unrelated to WT1.

Specifications:

• Intended Use: IVD
• By Letter: W
• Antigen: Recombinant full-length human WT1 protein
• Clone: rWT1/857
• Isotype: IgG1/kappa
• Positive Control: Mesothelioma, Normal Kidney, Wilms' tumor
• Species Reactivity: Human
• Source: Mouse Monoclonal