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Uroplakin III - Concentrate - 0.1 ml

SKU:
PBC-ACI3023A

Pack Size: 1

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Product Description

Uroplakin III is present in the urothelial surface membrane of human renal pelvis, ureter, bladder, and urethra. Uroplakin III [BC17] demonstrated a higher sensitivity compared with [AU1] on urothelial transitional cell carcinomas, in in-house studies. [BC17] staining was negative in all normal and neoplastic tissues except for bladder; hence it is highly specific to uroepithelial tumours and may be a useful tool in the discrimination of bladder, renal and prostate cancers. Loss of Uroplakin III expression in bladder cancers has been associated with higher grade, muscle-invasive cancer, and lymph vascular invasion. Uroplakin III [BC17] may be used in a panel of antibodies including GATA3, p63 and S100P.

Specifications:

• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: BC17, Biocare Clone
• Isotype: IgG1
• Antigen: Uroplakin III
• Localisation: Membrane and cytoplasmic
• Positive Control: Bladder cancer

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