Smoothelin - Predilute - 6.0 ml

Product Description

Smoothelin [R4A] is a mouse monoclonal antibody directed to the cytoskeletal component of smooth muscle cells (SMC) known as smoothelin. Smoothelin is exclusively expressed in fully differentiated (contractile) SMCs. Smoothelin antibody has been reported to be a useful tool in monitoring SMC differentiation; and may aid in the distinction of terminally differentiated smooth muscle cells, smooth muscle neoplasms of the gastrointestinal tract and the staging of bladder carcinoma. Cells with SMC-like characteristics, such as myofibroblasts and myoepithelial cells, as well as skeletal and cardiac muscle, do not contain smoothelin.

Specifications:

• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: R4A
• Isotype: IgG1
• Antigen: Smoothelin
• Localisation: Cytoplasmic
• Positive Control: Bladder or colon carcinomas