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Smooth Muscle Actin - Concentrate - 0.5 ml

SKU:
PBC-CM001B

Pack Size: 1

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Target:

  • Cat
  • Dog
  • Horse
  • Human
  • Mouse
  • Rat
  • Sheep

Product Description

This antibody recognises the alpha-smooth muscle isoform of actin. It shows no cross-reaction with actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric), and myocardium (alpha-myocardial). Its epitope is composed of the acetyl group and the first 4 amino acids on the N-terminal end of the peptidic chain of alpha-smooth actin. BIOCARE’s 1A4 MAb stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary glands are also stained as they also contain actin. This MAb is reportedly useful for identifying tumors arising from smooth muscle and myoepithelial cells.

Specifications:

• Intended Use: IVD
• Species Reactivity: Cat, Dog, Horse, Human, Mouse, Rat, Sheep
• Source: Mouse Monoclonal
• Clone: 1A4 (also known as asm-1)
• Isotype: IgG2a /kappa
• Antigen: Smooth Muscle Actin
• Localisation: Cytoplasmic
• Positive Control: Blood vessels, leiomyoma or leiomyosarcoma

Additional Information

Additional information is not currently available.

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