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SALL4 - Concentrate - 0.1 ml

SKU:
PBC-CM384A

Pack Size: 1

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Product Description

SALL4 is required for the maintenance of embryonic stem cell pluripotency by modulating Oct4. Studies support SALL4 as a sensitive and specific marker for seminomas and ovarian primitive germ-cell tumours. Studies have demonstrated that over 90% of tumour cells in intratubular germ-cell neoplasia’s and embryonal carcinomas show strong SALL4 staining. In addition, 100% of 31 yolk sac tumours (5 pediatric and 26 postpubertal) showed strong positive SALL4 staining of tumour cells but were negative for Oct4. SALL4 antibody is a promising pan germ-cell marker, with studies showing that it is superior to PLAP and Oct4 antibodies.

Specifications:

• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: 6E3
• Isotype: IgG1 /kappa
• Antigen: SALL4 (NP_065169, 954 a.a .~ 1054 a.a.) partial recombinant protein with GST tag
• Localisation: Nuclear
• Positive Control: Seminoma

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