Pan Cytokeratin Plus [AE1/AE3+8/18] - Predilute - 25 ml

Product Description

Pan Cytokeratin antibody Plus is a combination of [AE1/AE3] and Cytokeratin (CK) 8/18 [5D3] and can be used to detect most human epithelia. [AE1/AE3] recognizes acidic and basic subfamilies of cytokeratins, with molecular weights ranging from 40 to 67 kDa. CK8/18 [5D3] recognises Cytokeratin 8 and 18 intermediate filament proteins. In normal tissues, [5D3] recognises all simple and glandular epithelium. It has been observed that [AE1/AE3] has had problems marking certain tissue types and adenocarcinomas. The addition of CK 8/18 may remedy some of the limitations observed when staining with [AE1/AE3] alone.

Specifications:

• Intended Use: IVD
• Species Reactivity: Human, Mouse, Rat
• Source: Mouse Monoclonal
• Clone: AE1/AE3 + 5D3
• Isotype: IgG1
• Antigen: AE1/AE3 + CK8/18
• Localisation: Cytoplasmic
• Positive Control: Skin or adenocarcinoma