p63 + P504S (PIN) - ONCORE Pro - 60 Tests

Product Description

P504S is an enzyme in the ß-oxidation of branched-chain fatty acids. Expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. p63, a homolog of the tumour suppressor p53, encodes for different isotypes able to either transactivate p53 reporter genes (TAp63) or act as p53-dominant-negatives. Expression of p63 is detected in prostate basal epithelial nuclei in normal prostate; however, is negative in malignant tumours of the prostate gland. p63 + P504S antibody may be an extremely useful aid in diagnosing prostatic intraepithelial neoplasia (PIN), especially in difficult and limited tissues cases.

Specifications:

• Intended Use: RUO
• Species Reactivity: Human
• Source: Mouse Monoclonal, Rabbit Polyclonal
• Clone: 4A4 N/A
• Isotype: IgG, IgG2a/kappa
• Antigen: p63 P504S
• Localisation: Nuclear Granular Cytoplasm
• Positive Control: Normal prostate and prostate adenocarcinoma