p53 - intelliPATH - 10 ml

Product Description

p53 has been observed to act as both as a tumour-suppressor and transcription factor. p53 activation by DNA damage or other stress signals is reported to trigger DNA repair, cell-cycle arrest, or apoptosis. The nuclear p53 gene is located on chromosome 17p, a frequent site of allele loss in many tumours (60%) including breast, colon and lung. Studies have shown this high affinity p53 rabbit monoclonal is very specific and is superior to other p53 mouse monoclonal antibodies. p53 antibody recognizes both wild-type and mutant p53.

Specifications:

• Intended Use: IVD
• Source: Rabbit Monoclonal
• Clone: EP9
• Isotype: IgG
• Antigen: p53
• Localisation: Nuclear
• Positive Control: Breast and colon carcinomas