p40 (M) - 3X (Prostate)

Product Description

The mouse monoclonal antibody p40 [BC28] recognizes an epitope unique to the p40 protein and may have applications in cases where p63 has traditionally been used. To date, p63 [4A4] has been a frequently used marker of basal epithelium in normal prostate, with expression not typically observed in prostatic adenocarcinoma. A study has shown p40 (M) antibody staining of normal prostate glands and prostatic intraepithelial neoplasia (PIN) equivalent to p63, with no p40 staining observed in prostate cancer. p63 [4A4] recognizes both the p63 and p40 proteins. In contrast to the rabbit polyclonal p40 antibody, p40 [BC28] does not stain macrophages.

Specifications:

• Intended Use: IVD
• Format: Predilute
• Volume: 3.0 ml
• Source: Mouse Monoclonal
• Clone: BC28, Biocare Clone
• Isotype: IgG1
• Antigen: Amino Acids 5-17 of p40
• Localization: Nuclear
• Positive Control: Normal prostate or prostate cancer containing normal glands.
• Species Reactivity: Human