p120 Catenin - Concentrate - 0.1 ml

Product Description

p120 is a proliferation-associated nucleolar protein found in most human malignant tumours, but not in resting normal cells. In colorectal cancer the altered localisation of p120 Catenin corresponds with loss of cytoplasmic localisation of E-cadherin. Studies have shown accurate categorisation of ductal vs. lobular neoplasia in the breast was achieved with p120 staining. p120 expression further clarifies the separation of low-grade ductal carcinoma in situ from lobular neoplasia. Studies also have shown that altered expression of p120 Catenin antibody predicts poor outcome in invasive breast cancer.

Specifications:

• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: 98/pp120
• Isotype: IgG1
• Antigen: p120 catenin
• Localisation: Cytoplasmic and membrane
• Positive Control: Breast cancer