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NKX/MYC del-TECT Four Color FISH Probe

SKU:
PBC-PFR7030A

Pack Size: 1

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Product Description

NKX is a prostate-specific tumour suppressor gene and loss of a single allele may predispose to prostate carcinogenesis1. Studies have shown that the onset of MYC over expression and the subsequent development of prostatic intraepithelial neoplasia coincide with this reduction in NKX. Over-expression of MYC has been reported as an early oncogenic event driving prostatic cancer progression3. Data shows that NKX expression is highly, but not exclusively, specific for the prostate. Loss of NKX3.1 expression is strongly associated with hormone-refractory disease and advanced tumour stage in prostate cancer.

Specifications:

• Intended Use: RUO
• Volume: 100 µl
• Target: Prostate
• Colour: Aqua, Green, Orange, Red
• Chromosome: 8

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