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MYC (8q24) Orange + Copy Control 8 Green FISH Probe

SKU:
PBC-PFR7027A

Pack Size: 1

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Product Description

The MYC gene belongs to a family of transcription factors that under normal conditions it controls cell cycle progression 1. However, in multiple types of cancer, MYC is considered a Proto oncogene1. MYC gene deregulation is identified in multiple malignancies such as Burkitt’s lymphoma, diffuse large B-cell lymphoma, and B-cell lymphoma 2. MYC gene amplifications, rearrangements, and/or point mutations are considered the underlying mechanisms that induce MYC gene deregulation 1. Specifically, a MYC gene rearrangement is considered a prognostic marker in several cancer subtypes. MYC gene rearrangements can be identified using conventional cytogenetic techniques such as fluorescence in situ hybridization (FISH).

Specifications:

• Intended Use: RUO
• Volume: 100 µl
• Target: Breast, Cervical, CLL, Esophogeal, Gastric, Lymphoma, Prostate
• Colour: Green, Orange
• Chromosome: 8

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