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MDM2 (12q15) Red + Copy Control 12 Green FISH Probe


Pack Size: 1

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Product Description

The MDM2 gene is located in the chromosomal region 12q15 and encodes for an E3 ubiquitin ligase which acts as a major negative regulator of the tumour suppressor p531. Due to amplification of the respective chromosomal region, MDM2 is overexpressed in many human tumours such as soft tissue sarcomas, osteosarcomas2, gliomas, NSCLC, gastric and breast carcinomas.


• Intended Use: RUO
• Volume: 100 µl
• Colour: Green, Red
• Chromosome: 12

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