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Mart-1 Cocktail - Predilute - 6.0 ml


Pack Size: 1

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Product Description

The MART-1/Melan-A recognises a protein of 18 kDa, identified as MART-1 antibody (Melanoma Antigen Recognised by T cells 1) or Melan-A. MART-1 antibody recognises a subcellular fraction found in melanosomes. The antibody labels melanomas and tumours showing melanocytic differentiation. It does not mark neoplasms of epithelial origin, lymphomas or mesenchymal tumours. MART-1 is a useful addition to melanoma panels which are specific to melanocytic lesions. MART-1 is co-expressed with HMB45 in the majority of melanomas, as well as solely expressed in certain cases. Studies have shown that MART-1 is more sensitive than HMB45 when labelling metastatic melanomas.


• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: M2-7C10 + M2-9E3
• Isotype: IgG2b + IgG2b
• Antigen: Melan-A or MART-1
• Localisation: Cytoplasmic
• Positive Control: Melanoma

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