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Ki-67 + Caspase-3 - Predilute - 6.0 ml


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Product Description

Ki-67 + Caspase-3 can provide information on cell death vs. cell proliferation in the same tissue section. The Ki-67 nuclear antigen is associated with cell proliferation and is used to grade proliferation rates of tumours. Ki-67 is found throughout the cell cycle that includes the G1, S, G2, and M phases; but not the G0 phase. Apoptosis has gained central importance in the study of many biological processes, including neoplasia, neurodegenerative diseases, and development. Cleaved caspase-3 detects endogenous levels of the large fragment of activated caspase-3, a protease that mediates apoptosis. Caspase-3 does not cross react with other cleaved caspases.


• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal, Rabbit Polyclonal
• Clone: DVB-2
• Isotype : IgG1 (Ki-67 only)
• Antigen: Ki-67 and Caspase-3
• Localisation: Ki-67: (nuclear): brown Caspase-3: (cytoplasmic / nuclear): red
• Positive Control: Tonsil or Colon Cancer

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