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GATA-3 - ONCORE Pro - 60 Tests


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Product Description

GATA-3 antibody (GATA binding protein 3) is a member of the GATA family of transcription factors. GATA-3 appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 has a strong association with oestrogen receptor-alpha expression in breast cancer and evidence exists that GATA-3 may be used to predict response to hormonal therapy of breast cancer patients. GATA-3 has also been shown to be a novel marker for bladder cancer. In one study, GATA-3 stained 67% of 308 urothelial carcinomas but no prostate or renal carcinomas.


• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: L50-823
• Isotype: IgG1/kappa
• Antigen: Peptide between trans-activation and DNA-binding domains of GATA-3
• Localization: Nuclear
• Positive Control: Bladder cancer and breast cancer

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