E-cadherin (Mouse) - Predilute - 6.0 ml

Product Description

E-cadherin mouse antibody is a transmembrane glycoprotein that mediates epithelial cell-cell adhesion. The loss of E-cadherin can result in the disruption of cell clusters. It has been postulated in literature that E-cadherin may function as a tumour suppressor protein. Several studies have associated the loss of E-cadherin with metastasis and poor prognosis in invasive breast cancer. Additional studies have suggested that E-cadherin can help differentiate between ductal and lobular neoplasms of the breast. E-cadherin immunostaining has also been shown to be an independent predictor of disease progression in bladder cancer.

Specifications:

• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: HECD-1
• Isotype: IgG1
• Antigen: E-cadherin
• Localization: Cytoplasmic/membrane
• Positive Control: Breast cancer