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Desmoglein 3 - Predilute - 6.0 ml


Pack Size: 1

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Product Description

Desmoglein 3 Antibody (DSG3) is a component of desmosomes in vertebrate epithelial cells. This protein has been identified as the auto antigen of the skin blistering disease pemphigus vulgaris. Lung studies have shown that DSG3 had a sensitivity and specificity of 83% and 100%, respectively, in detecting squamous cell carcinoma (SqCC) vs. adenocarcinoma. Thus, DSG3 is a first-class marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Other studies have shown that DSG3 antibody expression in lung SqCC indicated a poor prognosis and portends a more aggressive clinical outcome.


• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: BC11, Biocare Clone
• Isotype: IgG1
• Antigen: Desmoglein 3
• Localization: Membrane
• Positive Control: Lung squamous cell carcinoma

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