Desmin - intelliPATH - 10 ml

Product Description

This MAb [D33] recognizes desmin antibody, a 53kDa intermediate filament (IF) protein. Studies have shown that [D33] is highly specific to desmin and shows no cross-reaction with other IF proteins. Studies have also shown D33 to be useful in identification of tumours of myogenic origin; it has been shown to react with leiomyosarcomas (smooth muscle) as well as rhabdomyosarcomas (striated muscle). Several studies have utilized desmin in a panel to aid in the classification of uterine sarcomas. Studies addressing desmoplastic reaction in colorectal and pancreatic cancers have demonstrated D33 to be a helpful marker of tumour invasion.

Specifications:

• Intended Use: IVD
• Species Reactivity: Human, Mouse, Rat
• Source: Mouse Monoclonal
• Clone: D33
• Isotype: IgG1 /kappa
• Antigen: Desmin
• Localization: Cytoplasmic
• Positive Control: Leiomyoma, leiomyosarcoma, rhabdomyosarcoma