Cytokeratin LMW (8/18) - Predilute - 6.0 ml

Product Description

Cytokeratin LMW (8/18) antibody [5D3] recognizes Cytokeratins (CK) 8 and 18 intermediate filament proteins. In normal tissues, [5D3] recognizes all simple and glandular epithelium. In neoplastic tissues, [5D3] may prove useful to aid in the identification of adenocarcinomas and some squamous cell carcinomas. It is generally negative in keratinizing squamous carcinomas. Studies suggest [5D3] can be used in conjunction with HMW CK to rule out squamous cell carcinoma. Studies have also shown CK 8/18 expression in squamous cell carcinomas of the oral cavity may indicate a decreased survival rate.

Specifications:

• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: 5D3
• Isotype: IgG1
• Antigen: CK 8/18 (LMW)
• Localization: Cytoplasmic
• Positive Control: Skin