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CK5/14 + p63 + P504S Multiplex IHC - Predilute - 6.0 ml


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Product Description

In prostate tissue, mRNA for CK5 and CK14 has been detected in the basal cells of normal glands and prostatic intraepithelial neoplasia (PIN), a precursor lesion to prostatic adenocarcinoma; however, expression of CK5 or CK14 was not identified in invasive prostatic adenocarcinoma. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumours of the prostate. In IHC, P504S has been shown to be a specific marker of prostatic adenocarcinoma. Additionally, prostate glands involved in PIN have been found to express P504S, whereas P504S was nearly undetectable in benign glands.

Formerly known as PIN-4®


• Intended Use: RUO
• Source: Mouse Monoclonal, Mouse Monoclonal, Mouse Monoclonal, Rabbit Polyclonal
• Isotype: IgG, IgG1/kappa, IgG2a/kappa, IgG3
• Antigen: CK14, CK5, P504S, p63
• Localization: Cytoplasmic, Granular cytoplasm, Nuclear
• Staining: Brown (DAB), Brown (DAB), Brown (DAB), Red (Warp Red)

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