BRCA-1 0.5ml

Product Description

Remarks
The BRCA-1 antibody gene codes for a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumour suppressor. Findings suggest that BRCA-1 antibody plays a protective role in epithelial cells undergoing high levels of proliferation in association with differentiation. Additional studies have shown that the complete loss of BRCA-1 nuclear expression and the correlation with poor prognostic markers in breast cancer imply that the altered BRCA-1 phenotype may provide an added prognostic parameter for breast cancer and could be applied as a potential rapid screening technique for BRCA-1 mutations.

Specifications:

• Intended Use: IVD
• Species Reactivity: Human
• Source: Mouse Monoclonal
• Clone: MS110
• Isotype: IgG1
• Antigen: BRCA-1
• Localization: Nuclear
• Positive Control: Breast cancer